The OSTEOMET project addresses an important and highly translational topic: the clinically relevant disease field of osteoporosis. Osteoporosis is a disease of the skeleton, in affected patients it manifests itself as an impaired bone structure with deficient properties.
The osteoporotic cell phenotype should be suppressed by functionalizing the metal implant with an/organic nanoparticle composition. By including vascular and immune cells, a more accurate and comprehensive evaluation of the responses at the cell-implant interface will be possible.
The results of this research offer the potential for improved post-implant treatment that is suitable for previously damaged and osteoporotic bone and that enhances regeneration of surrounding bone tissue. The Department Trauma Surgery at the University Medical School in Regensburg (UKR) and the New Technology Research Centre (NTC) at the University of West Bohemia in Pilsen form a joint research platform.
See more information about methodology and experimental program here: poster