The OSTEOMET project addresses an important and highly translational topic:
the clinically relevant disease field of osteoporosis. Osteoporosis is a
disease of the skeleton, in affected patients it manifests itself as an
impaired bone structure with deficient properties.
The osteoporotic cell phenotype should be suppressed by functionalizing the
metal implant with an/organic nanoparticle composition. By including vascular
and immune cells, a more accurate and comprehensive evaluation of the
responses at the cell-implant interface will be possible.
The results of this research offer the potential for improved post-implant
treatment that is suitable for previously damaged and osteoporotic bone and
that enhances regeneration of surrounding bone tissue. The Department Trauma Surgery at the University Medical School in Regensburg
(UKR) and the
New Technology Research Centre (NTC) at the University of West Bohemia in Pilsen form a joint research platform.
See more information about methodology and experimental program here:
poster
[cz].